Semaglutide 2mg

Semaglutide

Manufacturer: Hilma Biocare

Category: Injection 

Dose and quantity: 2mg/ml

Package: 2mg/vial

Form: Powder 

Active Substance: Semaglutide

Active Half-Life: 5-7 days 

Classification: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs)

Dosage: 0,5-1 mg a week

Water retention: No

Aromatization: No

Info: Semaglutide is a medication used primarily to treat type 2 diabetes. It belongs to a class of drugs called glucagon-like peptide-1 receptor agonists (GLP-1 RAs). Semaglutide works by mimicking the action of a naturally occurring hormone called GLP-1, which helps regulate blood sugar levels in the body. 

Effects:

Type 2 Diabetes Management: Semaglutide is primarily prescribed to adults with type 2 diabetes. It helps lower blood sugar levels by stimulating the release of insulin, slowing down digestion, and reducing the amount of glucose produced by the liver.

Once-Weekly Dosing: Semaglutide is available in different formulations, including a once-weekly injectable pen. The 5mg dose is typically the starting dose for many patients. Your healthcare provider may adjust the dose based on your individual response and needs.

Weight Management: Semaglutide has also been approved as a treatment for weight management in some countries, often in higher doses than 5mg. It can help with weight loss by reducing appetite and promoting a feeling of fullness.

Complementary Treatment: Semaglutide is usually prescribed alongside a healthy diet and regular exercise to achieve optimal blood sugar control. It is often used when other medications, such as metformin, do not provide adequate glucose control.

Blood Pressure and Lipid Control: Some studies suggest that Semaglutide may have additional benefits for reducing blood pressure and improving lipid profiles in people with type 2 diabetes, which can be important for cardiovascular health.

Adverse Effects:

Nausea: One of the most common side effects of Semaglutide is nausea. Some people may experience mild to moderate nausea, especially when they first start taking the medication. This side effect often improves over time.

Vomiting: Vomiting can occur in some individuals using Semaglutide, particularly during the initial stages of treatment.

Diarrhea: Diarrhea is another gastrointestinal side effect that may be associated with Semaglutide use.

Hypoglycemia: Semaglutide, when used in combination with other medications that lower blood sugar (such as sulfonylureas or insulin), can increase the risk of hypoglycemia (low blood sugar). It's important to follow your healthcare provider's instructions closely to avoid this complication.

Pancreatitis: Although rare, there have been reports of pancreatitis (inflammation of the pancreas) associated with the use of Semaglutide. Symptoms of pancreatitis include severe abdominal pain that may radiate to the back, nausea, and vomiting. If you experience these symptoms, you should seek medical attention immediately.

Thyroid Tumors: In clinical trials, an increased incidence of thyroid tumors, including cancer, has been observed in rodents treated with Semaglutide. However, the relevance of this finding to humans is not clear, and further studies are ongoing.

Gallbladder Disorders: Semaglutide may increase the risk of gallbladder-related events, such as gallstones or gallbladder inflammation.

Injection Site Reactions: Some people may experience mild reactions at the injection site, such as redness, itching, or swelling.

Allergic Reactions: While rare, some individuals may experience allergic reactions to Semaglutide, which can manifest as itching, rash, swelling, or difficulty breathing.

Dosage and Duration:

Semaglutide 0.5 mg or 1.0 mg: The starting dose for most people with type 2 diabetes is 0.5 mg injected once weekly. After 4 weeks, the dose may be increased to 1.0 mg once weekly if additional blood sugar control is needed.

Semaglutide is often used as a long-term treatment for individuals with type 2 diabetes. It is generally recommended for continuous use to help control blood sugar levels over an extended period.

Combination with Other Drugs:

It can be combined Semaglutide with other drugs such as Metformin, Sulfonylureas, Insulin, DPP-4 Inhibitors, DPP-4 inhibitors, SGLT-2 Inhibitors, Triple Therapy.